| 2022-11-02 16:30:4002/11/2022 | Santiago Wanderers  | 2 - 0 |  Deportes Santa Cruz | 16:30:4016:30 | N/A |
| 2022-10-24 18:00:5624/10/2022 | Deportes Santa Cruz | 2 - 1 |  Deportes Melipilla | 18:00:5618:00 | N/A |
| 2022-10-16 17:30:1416/10/2022 | San Luis de Quillota  | 0 - 0 | Deportes Santa Cruz | 17:30:1417:30 | N/A |
| 2022-10-10 20:00:3310/10/2022 | Deportes Santa Cruz | 4 - 0 |  Unión San Felipe | 20:00:3320:00 | N/A |
| 2022-10-03 15:30:5903/10/2022 | Deportes Recoleta  | 2 - 1 | Deportes Santa Cruz | 15:30:5915:30 | N/A |
| 2022-09-25 20:30:0625/09/2022 | Deportes Santa Cruz | 0 - 2 |  Deportes Puerto Montt | 20:30:0620:30 | N/A |
| 2022-09-12 20:30:4612/09/2022 | Deportes Copiapó  | 4 - 2 | Deportes Santa Cruz | 20:30:4620:30 | N/A |
| 2022-09-06 18:30:0206/09/2022 | Deportes Santa Cruz | 2 - 1 |  Rangers | 18:30:0218:30 | N/A |
| 2022-08-24 18:00:2324/08/2022 | Universidad de Concepción  | 3 - 2 | Deportes Santa Cruz | 18:00:2318:00 | N/A |
| 2022-08-15 15:00:4615/08/2022 | Deportes Santa Cruz | 1 - 0 |  Deportes Iquique | 15:00:4615:00 | N/A |
| 2022-08-08 12:30:4308/08/2022 | A.C. Barnechea  | 2 - 0 | Deportes Santa Cruz | 12:30:4312:30 | N/A |
| 2022-07-31 20:30:2231/07/2022 | Deportes Santa Cruz | 1 - 1 |  Cobreloa | 20:30:2220:30 | N/A |
| 2022-07-26 18:00:3126/07/2022 | Deportes Santa Cruz | 2 - 0 |  Arturo Fernández Vial | 18:00:3118:00 | N/A |
| 2022-07-16 11:00:4716/07/2022 | Magallanes  | 0 - 0 | Deportes Santa Cruz | 11:00:4711:00 | N/A |
| 2022-07-08 18:00:1708/07/2022 | Deportes Santa Cruz | 1 - 0 |  Santiago Morning | 18:00:1718:00 | N/A |
| 2022-07-02 12:30:3802/07/2022 | Deportes Temuco  | 1 - 1 | Deportes Santa Cruz | 12:30:3812:30 | N/A |
| 2022-06-02 15:00:4202/06/2022 | Cobreloa | 1 - 0 | Deportes Santa Cruz | 15:00:4215:00 | N/A |
| 2022-05-27 18:00:4827/05/2022 | Deportes Santa Cruz | 2 - 0 | Santiago Wanderers | 18:00:4818:00 | N/A |
| 2022-05-22 17:30:4922/05/2022 | Deportes Melipilla | 1 - 0 | Deportes Santa Cruz | 17:30:4917:30 | N/A |
| 2022-05-17 20:30:3717/05/2022 | Deportes Santa Cruz | 2 - 0 | San Luis de Quillota | 20:30:3720:30 | N/A |
| 2022-05-12 18:00:5512/05/2022 | Unión San Felipe | 2 - 1 | Deportes Santa Cruz | 18:00:5518:00 | N/A |
| 2022-04-03 12:30:4703/04/2022 | Deportes Iquique | 2 - 2 | Deportes Santa Cruz | 12:30:4712:30 | N/A |
| 2022-03-23 20:30:5323/03/2022 | Deportes Santa Cruz | 1 - 1 | A.C. Barnechea | 20:30:5320:30 | N/A |
| 2022-03-07 18:30:0707/03/2022 | Arturo Fernández Vial | 1 - 0 | Deportes Santa Cruz | 18:30:0718:30 | N/A |
| 2021-01-17 10:00:5017/01/2021 | Deportes Santa Cruz | 3 - 2 |  Deportes Valdivia | 10:00:5010:00 | N/A |
| 2021-01-12 18:00:2812/01/2021 | Magallanes | 2 - 0 | Deportes Santa Cruz | 18:00:2818:00 | N/A |
| 2020-12-27 21:30:4227/12/2020 | Deportes Santa Cruz | 1 - 3 |  Ñublense | 21:30:4221:30 | N/A |
| 2020-12-23 20:30:0523/12/2020 | Deportes Melipilla | 0 - 0 | Deportes Santa Cruz | 20:30:0520:30 | N/A |
| 2020-12-14 20:15:3514/12/2020 | Rangers | 4 - 1 | Deportes Santa Cruz | 20:15:3520:15 | N/A |
| 2020-12-10 10:00:0810/12/2020 | Deportes Santa Cruz | 4 - 1 | Cobreloa | 10:00:0810:00 | N/A |
| 2020-12-06 10:00:1406/12/2020 | Deportes Temuco | 2 - 1 | Deportes Santa Cruz | 10:00:1410:00 | N/A |
| 2020-11-30 10:30:4030/11/2020 | Deportes Copiapó | 2 - 0 | Deportes Santa Cruz | 10:30:4010:30 | N/A |
| 2020-11-24 18:00:2124/11/2020 | Deportes Santa Cruz | 0 - 2 |  San Marcos de Arica | 18:00:2118:00 | N/A |
| 2020-10-08 15:00:0408/10/2020 | San Marcos de Arica | 2 - 1 | Deportes Santa Cruz | 15:00:0415:00 | N/A |
| 2020-10-04 19:00:2404/10/2020 | Deportes Santa Cruz | 0 - 3 | Magallanes | 19:00:2419:00 | N/A |
| 2020-10-01 16:00:0201/10/2020 | A.C. Barnechea | 2 - 3 | Deportes Santa Cruz | 16:00:0216:00 | N/A |
| 2020-09-28 15:00:0028/09/2020 | Deportes Santa Cruz | 2 - 1 | Santiago Morning | 15:00:0015:00 | N/A |
| 2020-09-23 16:00:1023/09/2020 | San Luis de Quillota | 0 - 0 | Deportes Santa Cruz | 16:00:1016:00 | N/A |
| 2020-09-20 13:30:3420/09/2020 | Deportes Santa Cruz | 0 - 2 | Deportes Temuco | 13:30:3413:30 | N/A |
| 2020-09-14 13:30:1814/09/2020 | Ñublense | 2 - 2 | Deportes Santa Cruz | 13:30:1813:30 | N/A |
| 2020-09-10 13:30:0310/09/2020 | Deportes Santa Cruz | 0 - 1 | Deportes Puerto Montt | 13:30:0313:30 | N/A |
| 2020-09-06 12:00:3706/09/2020 | Cobreloa | 0 - 1 | Deportes Santa Cruz | 12:00:3712:00 | N/A |
| 2020-08-31 15:00:1831/08/2020 | Deportes Santa Cruz | 2 - 4 | Deportes Melipilla | 15:00:1815:00 | N/A |
| 2020-03-17 20:30:1317/03/2020 | Unión San Felipe | 1 - 1 | Deportes Santa Cruz | 20:30:1320:30 | N/A |
| 2020-03-01 18:00:2701/03/2020 | Deportes Santa Cruz | 0 - 2 | Rangers | 18:00:2718:00 | N/A |
| 2020-02-23 19:00:4723/02/2020 | Deportes Valdivia | 1 - 0 | Deportes Santa Cruz | 19:00:4719:00 | N/A |
Argentina
