| 2022-11-02 16:30:4002/11/2022 | Santiago Wanderers  | 2 - 0 |  Deportes Santa Cruz | 16:30:4016:30 | N/A |
| 2022-10-15 17:30:5315/10/2022 | Universidad de Concepción  | 1 - 1 | Santiago Wanderers | 17:30:5317:30 | N/A |
| 2022-10-08 20:00:0008/10/2022 | Santiago Wanderers | 2 - 2 |  Cobreloa | 20:00:0020:00 | N/A |
| 2022-10-03 15:30:1403/10/2022 | A.C. Barnechea  | 1 - 0 | Santiago Wanderers | 15:30:1415:30 | N/A |
| 2022-09-25 15:00:4925/09/2022 | Santiago Wanderers | 0 - 0 |  Deportes Recoleta | 15:00:4915:00 | N/A |
| 2022-09-10 12:30:1210/09/2022 | Unión San Felipe  | 2 - 3 | Santiago Wanderers | 12:30:1212:30 | N/A |
| 2022-09-06 15:30:1206/09/2022 | Santiago Wanderers | 2 - 2 |  Deportes Melipilla | 15:30:1215:30 | N/A |
| 2022-08-27 20:30:0827/08/2022 | Deportes Puerto Montt  | 1 - 1 | Santiago Wanderers | 20:30:0820:30 | N/A |
| 2022-08-21 15:00:2221/08/2022 | Santiago Wanderers | 1 - 0 |  Deportes Copiapó | 15:00:2215:00 | N/A |
| 2022-08-16 18:00:2216/08/2022 | Santiago Wanderers | 3 - 0 |  Deportes Temuco | 18:00:2218:00 | N/A |
| 2022-08-12 15:00:1612/08/2022 | Magallanes  | 0 - 1 | Santiago Wanderers | 15:00:1615:00 | N/A |
| 2022-08-07 11:00:2707/08/2022 | Santiago Wanderers | 2 - 2 |  Arturo Fernández Vial | 11:00:2711:00 | N/A |
| 2022-08-01 20:30:5301/08/2022 | Rangers  | 1 - 2 | Santiago Wanderers | 20:30:5320:30 | N/A |
| 2022-07-25 18:00:1725/07/2022 | Santiago Wanderers | 1 - 2 |  San Luis de Quillota | 18:00:1718:00 | N/A |
| 2022-07-15 15:30:4115/07/2022 | Santiago Morning  | 1 - 2 | Santiago Wanderers | 15:30:4115:30 | N/A |
| 2022-07-01 21:00:5801/07/2022 | Deportes Iquique  | 2 - 1 | Santiago Wanderers | 21:00:5821:00 | N/A |
| 2022-06-09 18:00:4409/06/2022 | Santiago Wanderers | 0 - 1 | Unión San Felipe | 18:00:4418:00 | N/A |
| 2022-06-05 15:30:1105/06/2022 | Santiago Wanderers | 2 - 0 | Deportes Iquique | 15:30:1115:30 | N/A |
| 2022-05-27 18:00:4827/05/2022 | Deportes Santa Cruz | 2 - 0 | Santiago Wanderers | 18:00:4818:00 | N/A |
| 2022-05-16 18:00:2716/05/2022 | Santiago Wanderers | 0 - 0 | Universidad de Concepción | 18:00:2718:00 | N/A |
| 2022-05-12 20:30:2312/05/2022 | Cobreloa | 1 - 1 | Santiago Wanderers | 20:30:2320:30 | N/A |
| 2022-05-06 18:00:2206/05/2022 | Santiago Wanderers | 1 - 3 | A.C. Barnechea | 18:00:2218:00 | N/A |
| 2022-04-30 19:30:5830/04/2022 | Deportes Recoleta | 1 - 2 | Santiago Wanderers | 19:30:5819:30 | N/A |
| 2022-04-20 18:00:2320/04/2022 | Deportes Melipilla | 2 - 0 | Santiago Wanderers | 18:00:2318:00 | N/A |
| 2022-04-16 12:30:4216/04/2022 | Santiago Wanderers | 2 - 0 | Deportes Puerto Montt | 12:30:4212:30 | N/A |
| 2022-04-09 12:30:4409/04/2022 | Deportes Copiapó | 1 - 1 | Santiago Wanderers | 12:30:4412:30 | N/A |
| 2022-04-03 12:30:4403/04/2022 | Santiago Wanderers | 0 - 2 | Magallanes | 12:30:4412:30 | N/A |
| 2022-03-22 18:00:5722/03/2022 | Arturo Fernández Vial | 0 - 0 | Santiago Wanderers | 18:00:5718:00 | N/A |
| 2022-03-16 20:30:3116/03/2022 | Santiago Wanderers | 1 - 3 | Rangers | 20:30:3120:30 | N/A |
| 2022-03-09 20:30:5309/03/2022 | San Luis de Quillota | 1 - 1 | Santiago Wanderers | 20:30:5320:30 | N/A |
| 2022-03-01 20:30:3201/03/2022 | Santiago Wanderers | 2 - 2 | Santiago Morning | 20:30:3220:30 | N/A |
| 2022-02-21 20:30:2921/02/2022 | Deportes Temuco | 1 - 0 | Santiago Wanderers | 20:30:2920:30 | N/A |
Argentina
