| 2021-11-13 18:00:1113/11/2021 | Deportes Copiapó  | 2 - 0 |  Universidad de Concepción | 18:00:1118:00 | N/A |
| 2021-11-06 20:30:3906/11/2021 | Universidad de Concepción | 2 - 0 |  Arturo Fernández Vial | 20:30:3920:30 | N/A |
| 2021-10-31 16:00:3231/10/2021 | San Marcos de Arica  | 0 - 0 | Universidad de Concepción | 16:00:3216:00 | N/A |
| 2021-10-25 18:30:4525/10/2021 | Universidad de Concepción | 0 - 2 |  San Luis de Quillota | 18:30:4518:30 | N/A |
| 2021-10-02 18:00:4402/10/2021 | Deportes Temuco  | 2 - 2 | Universidad de Concepción | 18:00:4418:00 | N/A |
| 2021-09-27 20:30:0227/09/2021 | Universidad de Concepción | 0 - 0 |  Deportes Puerto Montt | 20:30:0220:30 | N/A |
| 2021-09-23 18:30:3623/09/2021 | Unión San Felipe  | 1 - 0 | Universidad de Concepción | 18:30:3618:30 | N/A |
| 2021-09-16 20:30:5716/09/2021 | Universidad de Concepción | 0 - 1 |  Coquimbo Unido | 20:30:5720:30 | N/A |
| 2021-09-06 20:00:4506/09/2021 | Rangers  | 1 - 0 | Universidad de Concepción | 20:00:4520:00 | N/A |
| 2021-09-01 20:00:3301/09/2021 | Universidad de Concepción | 0 - 0 |  Cobreloa | 20:00:3320:00 | N/A |
| 2021-08-16 19:00:4816/08/2021 | Universidad de Concepción | 1 - 2 | Deportes Copiapó | 19:00:4819:00 | N/A |
| 2021-08-09 18:00:2609/08/2021 | Arturo Fernández Vial | 0 - 0 | Universidad de Concepción | 18:00:2618:00 | N/A |
| 2021-08-03 18:00:4003/08/2021 | Universidad de Concepción | 3 - 1 | San Marcos de Arica | 18:00:4018:00 | N/A |
| 2021-07-28 18:30:3428/07/2021 | Universidad de Concepción | 1 - 1 |  Magallanes | 18:30:3418:30 | N/A |
| 2021-07-22 20:30:5022/07/2021 | San Luis de Quillota | 1 - 0 | Universidad de Concepción | 20:30:5020:30 | N/A |
| 2021-07-14 12:30:0814/07/2021 | A.C. Barnechea  | 1 - 2 | Universidad de Concepción | 12:30:0812:30 | N/A |
| 2021-06-06 14:30:4906/06/2021 | Deportes Iquique  | 5 - 1 | Universidad de Concepción | 14:30:4914:30 | N/A |
| 2021-05-29 20:00:3929/05/2021 | Universidad de Concepción | 3 - 1 | Deportes Temuco | 20:00:3920:00 | N/A |
| 2021-05-23 18:00:0723/05/2021 | Deportes Puerto Montt | 2 - 2 | Universidad de Concepción | 18:00:0718:00 | N/A |
| 2021-05-18 18:00:4218/05/2021 | Universidad de Concepción | 0 - 0 | Unión San Felipe | 18:00:4218:00 | N/A |
| 2021-05-10 12:00:2510/05/2021 | Coquimbo Unido | 1 - 0 | Universidad de Concepción | 12:00:2512:00 | N/A |
| 2021-05-01 20:30:0601/05/2021 | Universidad de Concepción | 3 - 2 | Rangers | 20:30:0620:30 | N/A |
| 2021-04-26 11:00:2026/04/2021 | Cobreloa | 2 - 4 | Universidad de Concepción | 11:00:2011:00 | N/A |
| 2021-04-18 18:00:2818/04/2021 | Deportes Santa Cruz  | 2 - 2 | Universidad de Concepción | 18:00:2818:00 | N/A |
| 2021-04-12 17:00:4912/04/2021 | Universidad de Concepción | 3 - 3 |  Santiago Morning | 17:00:4917:00 | N/A |
Paraguay
