| 2021-11-12 19:00:3712/11/2021 | San Luis de Quillota  | 2 - 1 |  A.C. Barnechea | 19:00:3719:00 | N/A |
| 2021-11-06 17:30:3606/11/2021 | Magallanes  | 3 - 3 | San Luis de Quillota | 17:30:3617:30 | N/A |
| 2021-10-30 21:00:2630/10/2021 | San Luis de Quillota | 0 - 0 |  Coquimbo Unido | 21:00:2621:00 | N/A |
| 2021-10-25 18:30:4525/10/2021 | Universidad de Concepción  | 0 - 2 | San Luis de Quillota | 18:30:4518:30 | N/A |
| 2021-10-20 19:30:3820/10/2021 | San Luis de Quillota | 2 - 2 |  Santiago Morning | 19:30:3819:30 | N/A |
| 2021-10-12 18:00:5512/10/2021 | San Luis de Quillota | 0 - 0 |  Deportes Santa Cruz | 18:00:5518:00 | N/A |
| 2021-10-08 19:00:2008/10/2021 | San Marcos de Arica  | 1 - 2 | San Luis de Quillota | 19:00:2019:00 | N/A |
| 2021-10-01 20:00:3201/10/2021 | San Luis de Quillota | 1 - 0 |  Cobreloa | 20:00:3220:00 | N/A |
| 2021-09-26 14:00:4726/09/2021 | Deportes Copiapó  | 4 - 1 | San Luis de Quillota | 14:00:4714:00 | N/A |
| 2021-09-22 18:30:3122/09/2021 | Arturo Fernández Vial  | 2 - 2 | San Luis de Quillota | 18:30:3118:30 | N/A |
| 2021-09-15 20:00:0715/09/2021 | San Luis de Quillota | 1 - 1 |  Deportes Iquique | 20:00:0720:00 | N/A |
| 2021-09-12 16:30:2912/09/2021 | San Luis de Quillota | 3 - 2 | Arturo Fernández Vial | 16:30:2916:30 | N/A |
| 2021-09-06 20:00:2006/09/2021 | Unión San Felipe  | 1 - 1 | San Luis de Quillota | 20:00:2020:00 | N/A |
| 2021-09-01 11:30:0401/09/2021 | San Luis de Quillota | 0 - 1 |  Deportes Puerto Montt | 11:30:0411:30 | N/A |
| 2021-08-28 17:30:1528/08/2021 | Rangers  | 0 - 1 | San Luis de Quillota | 17:30:1517:30 | N/A |
| 2021-08-23 16:30:3223/08/2021 | San Luis de Quillota | 1 - 1 |  Deportes Temuco | 16:30:3216:30 | N/A |
| 2021-08-17 14:00:1617/08/2021 | A.C. Barnechea | 0 - 0 | San Luis de Quillota | 14:00:1614:00 | N/A |
| 2021-08-09 20:30:4209/08/2021 | San Luis de Quillota | 1 - 1 | Magallanes | 20:30:4220:30 | N/A |
| 2021-07-31 20:00:3331/07/2021 | Coquimbo Unido | 0 - 1 | San Luis de Quillota | 20:00:3320:00 | N/A |
| 2021-07-22 20:30:5022/07/2021 | San Luis de Quillota | 1 - 0 | Universidad de Concepción | 20:30:5020:30 | N/A |
| 2021-07-15 15:00:2515/07/2021 | Santiago Morning | 0 - 0 | San Luis de Quillota | 15:00:2515:00 | N/A |
| 2021-07-11 15:30:2411/07/2021 | Deportes Santa Cruz | 2 - 0 | San Luis de Quillota | 15:30:2415:30 | N/A |
| 2021-06-07 11:00:5607/06/2021 | San Luis de Quillota | 3 - 0 | San Marcos de Arica | 11:00:5611:00 | N/A |
| 2021-05-30 12:00:3830/05/2021 | Cobreloa | 1 - 0 | San Luis de Quillota | 12:00:3812:00 | N/A |
| 2021-05-24 20:30:0224/05/2021 | San Luis de Quillota | 1 - 2 | Deportes Copiapó | 20:30:0220:30 | N/A |
| 2021-05-09 12:00:2909/05/2021 | Deportes Iquique | 0 - 0 | San Luis de Quillota | 12:00:2912:00 | N/A |
| 2021-05-03 15:30:0603/05/2021 | San Luis de Quillota | 1 - 2 | Unión San Felipe | 15:30:0615:30 | N/A |
| 2021-04-26 12:00:0126/04/2021 | Deportes Puerto Montt | 2 - 1 | San Luis de Quillota | 12:00:0112:00 | N/A |
| 2021-04-18 18:00:3018/04/2021 | San Luis de Quillota | 0 - 1 | Rangers | 18:00:3018:00 | N/A |
| 2021-04-04 11:00:2704/04/2021 | Deportes Temuco | 2 - 2 | San Luis de Quillota | 11:00:2711:00 | N/A |
Argentina
