| 2021-11-13 15:30:5913 noviembre, 2021 | Cobreloa  | 4 - 1 | Rangers | 15:30:5915:30 | N/A |
| 2021-11-06 20:30:046 noviembre, 2021 | Deportes Santa Cruz | 2 - 2 | Cobreloa | 20:30:0420:30 | N/A |
| 2021-11-01 20:30:021 noviembre, 2021 | Cobreloa | 0 - 2 | Deportes Temuco | 20:30:0220:30 | N/A |
| 2021-10-27 20:00:3027 octubre, 2021 | Deportes Puerto Montt | 0 - 0 | Cobreloa | 20:00:3020:00 | N/A |
| 2021-10-20 19:00:4520 octubre, 2021 | Arturo Fernández Vial | 3 - 2 | Cobreloa | 19:00:4519:00 | N/A |
| 2021-10-16 15:00:1916 octubre, 2021 | Cobreloa | 2 - 0 | Deportes Copiapó | 15:00:1915:00 | N/A |
| 2021-10-12 20:30:0112 octubre, 2021 | Deportes Iquique | 1 - 0 | Cobreloa | 20:30:0120:30 | N/A |
| 2021-10-06 18:00:426 octubre, 2021 | Cobreloa | 2 - 1 | Magallanes | 18:00:4218:00 | N/A |
| 2021-10-01 20:00:321 octubre, 2021 | San Luis de Quillota | 1 - 0 | Cobreloa | 20:00:3220:00 | N/A |
| 2021-09-26 14:00:0726 septiembre, 2021 | Cobreloa | 1 - 2 | Arturo Fernández Vial | 14:00:0714:00 | N/A |
| 2021-09-22 12:00:2122 septiembre, 2021 | Santiago Morning | 2 - 1 | Cobreloa | 12:00:2112:00 | N/A |
| 2021-09-16 14:00:4516 septiembre, 2021 | Cobreloa | 2 - 1 | Unión San Felipe | 14:00:4514:00 | N/A |
| 2021-09-06 17:00:196 septiembre, 2021 | Coquimbo Unido | 2 - 1 | Cobreloa | 17:00:1917:00 | N/A |
| 2021-09-01 20:00:331 septiembre, 2021 | Universidad de Concepción | 0 - 0 | Cobreloa | 20:00:3320:00 | N/A |
| 2021-08-29 12:00:5829 agosto, 2021 | Cobreloa | - | San Marcos de Arica | 12:00:5812:00 | N/A |
| 2021-08-24 11:00:5624 agosto, 2021 | A.C. Barnechea | 1 - 1 | Cobreloa | 11:00:5611:00 | N/A |
| 2021-08-16 16:30:3716 agosto, 2021 | Rangers | 4 - 0 | Cobreloa | 16:30:3716:30 | N/A |
| 2021-08-08 11:00:578 agosto, 2021 | Cobreloa | 0 - 1 | Deportes Santa Cruz | 11:00:5711:00 | N/A |
| 2021-07-14 18:00:3914 julio, 2021 | Deportes Copiapó | 0 - 0 | Cobreloa | 18:00:3918:00 | N/A |
| 2021-06-07 12:30:367 junio, 2021 | Magallanes | 2 - 2 | Cobreloa | 12:30:3612:30 | N/A |
| 2021-05-30 12:00:3830 mayo, 2021 | Cobreloa | 1 - 0 | San Luis de Quillota | 12:00:3812:00 | N/A |
| 2021-05-09 20:30:269 mayo, 2021 | Unión San Felipe | 0 - 0 | Cobreloa | 20:30:2620:30 | N/A |
| 2021-05-03 18:00:573 mayo, 2021 | Cobreloa | 1 - 1 | Coquimbo Unido | 18:00:5718:00 | N/A |
| 2021-04-26 11:00:2026 abril, 2021 | Cobreloa | 2 - 4 | Universidad de Concepción | 11:00:2011:00 | N/A |
| 2021-04-18 17:00:0418 abril, 2021 | San Marcos de Arica | 0 - 3 | Cobreloa | 17:00:0417:00 | N/A |
| 2021-04-04 11:00:114 abril, 2021 | Cobreloa | 1 - 2 | A.C. Barnechea | 11:00:1111:00 | N/A |
| 2021-01-12 10:00:3112 enero, 2021 | Cobreloa | 1 - 1 | Deportes Copiapó | 10:00:3110:00 | N/A |
| 2021-01-06 10:00:466 enero, 2021 | Cobreloa | 6 - 0 | Deportes Valdivia | 10:00:4610:00 | N/A |
| 2020-12-30 10:00:3530 diciembre, 2020 | Cobreloa | 0 - 0 - 0 - 0 | Deportes Melipilla | 10:00:3510:00 | N/A |
| 2020-12-22 18:00:3222 diciembre, 2020 | Magallanes | 1 - 1 - 1 - 1 | Cobreloa | 18:00:3218:00 | N/A |
| 2020-12-18 10:00:1818 diciembre, 2020 | Cobreloa | 1 - 1 - 1 - 1 | Deportes Puerto Montt | 10:00:1810:00 | N/A |
| 2020-12-10 10:00:0810 diciembre, 2020 | Deportes Santa Cruz | 4 - 1 - 4 - 1 | Cobreloa | 10:00:0810:00 | N/A |
| 2020-12-06 10:00:046 diciembre, 2020 | Cobreloa | 4 - 2 - 4 - 2 | Ñublense | 10:00:0410:00 | N/A |
| 2020-11-25 10:30:1325 noviembre, 2020 | Unión San Felipe | 0 - 0 - 0 - 0 | Cobreloa | 10:30:1310:30 | N/A |
| 2020-11-21 10:00:5521 noviembre, 2020 | Cobreloa | 2 - 0 - 2 - 0 | A.C. Barnechea | 10:00:5510:00 | N/A |
| 2020-11-16 11:00:5616 noviembre, 2020 | Cobreloa | 3 - 0 - 3 - 0 | Rangers | 11:00:5611:00 | N/A |
| 2020-11-12 11:00:1512 noviembre, 2020 | San Luis de Quillota | 0 - 1 - 0 - 1 | Cobreloa | 11:00:1511:00 | N/A |
| 2020-11-03 14:00:183 noviembre, 2020 | San Marcos de Arica | 3 - 1 - 3 - 1 | Cobreloa | 14:00:1814:00 | N/A |
| 2020-10-28 11:00:2928 octubre, 2020 | Cobreloa | 2 - 3 - 2 - 3 | Santiago Morning | 11:00:2911:00 | N/A |
Chile
