| 2021-11-13 18:00:0613 noviembre, 2021 | San Marcos de Arica  | 0 - 0 | Deportes Santa Cruz | 18:00:0618:00 | N/A |
| 2021-11-01 18:00:551 noviembre, 2021 | Deportes Santa Cruz | 2 - 0 | A.C. Barnechea | 18:00:5518:00 | N/A |
| 2021-10-12 18:00:5512 octubre, 2021 | San Luis de Quillota | 0 - 0 | Deportes Santa Cruz | 18:00:5518:00 | N/A |
| 2021-10-08 18:30:368 octubre, 2021 | Deportes Santa Cruz | 1 - 2 | Deportes Copiapó | 18:30:3618:30 | N/A |
| 2021-10-03 12:30:443 octubre, 2021 | Deportes Iquique | 6 - 1 | Deportes Santa Cruz | 12:30:4412:30 | N/A |
| 2021-09-28 18:30:5028 septiembre, 2021 | Deportes Santa Cruz | 0 - 1 | Unión San Felipe | 18:30:5018:30 | N/A |
| 2021-09-23 21:00:1123 septiembre, 2021 | Coquimbo Unido | 0 - 0 | Deportes Santa Cruz | 21:00:1121:00 | N/A |
| 2021-09-14 16:30:5914 septiembre, 2021 | Deportes Santa Cruz | 1 - 0 | Deportes Temuco | 16:30:5916:30 | N/A |
| 2021-09-05 12:00:415 septiembre, 2021 | Deportes Puerto Montt | 2 - 2 | Deportes Santa Cruz | 12:00:4112:00 | N/A |
| 2021-08-31 20:00:4731 agosto, 2021 | Deportes Santa Cruz | 1 - 1 | Santiago Morning | 20:00:4720:00 | N/A |
| 2021-08-27 18:30:1627 agosto, 2021 | Universidad de Concepción | 0 - 1 | Deportes Santa Cruz | 18:30:1618:30 | N/A |
| 2021-08-22 15:00:3422 agosto, 2021 | Arturo Fernández Vial | 2 - 1 | Deportes Santa Cruz | 15:00:3415:00 | N/A |
| 2021-08-15 11:30:1915 agosto, 2021 | Deportes Santa Cruz | 2 - 0 | San Marcos de Arica | 11:30:1911:30 | N/A |
| 2021-08-08 11:00:578 agosto, 2021 | Cobreloa | 0 - 1 | Deportes Santa Cruz | 11:00:5711:00 | N/A |
| 2021-08-03 14:00:413 agosto, 2021 | A.C. Barnechea | 0 - 0 | Deportes Santa Cruz | 14:00:4114:00 | N/A |
| 2021-07-24 15:00:5224 julio, 2021 | Deportes Santa Cruz | 2 - 3 | Arturo Fernández Vial | 15:00:5215:00 | N/A |
| 2021-07-21 15:30:2621 julio, 2021 | Deportes Santa Cruz | 2 - 0 | Magallanes | 15:30:2615:30 | N/A |
| 2021-07-15 15:00:1215 julio, 2021 | Rangers | 1 - 3 | Deportes Santa Cruz | 15:00:1215:00 | N/A |
| 2021-07-11 15:30:2411 julio, 2021 | Deportes Santa Cruz | 2 - 0 | San Luis de Quillota | 15:30:2415:30 | N/A |
| 2021-06-07 12:00:597 junio, 2021 | Deportes Copiapó | 2 - 0 | Deportes Santa Cruz | 12:00:5912:00 | N/A |
| 2021-05-18 20:30:1118 mayo, 2021 | Deportes Santa Cruz | 1 - 7 | Coquimbo Unido | 20:30:1120:30 | N/A |
Chile
Chile
